Duped into thinking the world is coming to an end, Hank the Cowdog winds up in town for some more adventures including getting in and out of a case of "soap hydrophobia."
While working on a mysterious case involving disappearing eggs and a fiddle-playing fox named Frankie, Hank the Cowdog falls for Miss Beulah, the beautiful collie.
When Hank learns about a tool thief who uses a monkey to help him steal, Hank finds himself face-to-face with the primate on his ranch and must figure out how to stop the thief.
Hank the Cowdog, Head of Ranch Security, gets stuck in a trap set for whoever has been stealing feed from the feed shed and needs the help of Eddy the raccoon, a prime suspect.
In the course of his job as Head of Ranch Security, Hank the dog is asked to guard five chicks, despite the fact that poultry is his favorite kind of dinner.
Hank the Cowdog, Head of Ranch Security, and assistant deputy Drover engage in an epic battle with the coyotes, Rip and Snort, as they all seek some meaty treats.
When Slim is left to take care of the ranch and little Alfred, who has the measles, he gets sick himself and a freak blizzard sets in, so it is up Hank to try to keep things under control.
Hank the Cowdog tries to help when a burglar comes around Slim's house, but Hank is not sure he has what it take to bring the criminal down after he is sprayed by his super-stinky weapon, a skunk.