Private investigator Regan Reilly, in New York to attend a crime conference organized by her celebrity-author mother, is recruited by a friend to investigate the suspicious deaths of two members of the Settlers' Club on Gramercy Park who had promised to donate a cache of valuable diamonds to save the failing organization.

Returning home from their honeymoon to discover that their neighbor has put his Manhattan apartment up for sale, Regan Reilly and her husband Jack decide to buy it to enlarge their own loft, but the renovation process spawns its own set of problems and an unexpected case.

Private detective Regan Reilly investigates the theft of a number of wedding gowns, including her own, while her fiancé Jack, head of the NYPD Major Case Squad, tries to solve a series of bank robberies, unaware that the two cases are intertwined.